What Is Good Brain Food?

http://www.source-omega.com/shop/omega-3--122.htm - vegan DHA. It's where fish get their DHA. Fish are purchasing it left and right.

http://www.psychologytoday.com/articles/200310/what-is-good-brain-food

The health of your brain depends not only on how much (or little) fat you eat but on what kind it is. Intellectual performance requires the specific type of fat found most commonly in fish, known as omega-3 fatty acids. Even diets that adhere to commonly recommended levels of fats, but the wrong kind, can undermine intelligence. What makes this finding awkward is that certain oils widely touted as healthy for the heart are especially troublesome for the mind.

Omega-3s are known to be particularly crucial constituents of the outer membrane of brain cells. It is through the fat-rich cell membrane that all nerve signals must pass. In addition, as learning and memory forge new connections between nerve cells, new membranes must be formed to sheathe them. All brain cell membranes continuously need to refresh themselves with a new supply of fatty acids. A growing amount of research suggests that the omega-3s are best suited for optimal brain function.

Natalie Portman Sexy Pregnant Ex-Vegan

I'm dying from a load of work, but I had to post this.

I recently learned that Natalie Portman recently started eating eggs and dairy because she craved them during pregnancy. Good! (Update: I found out that she has had her baby. I don't keep up with celebrity news. Don't give a hoot. But anyway, this post is still relevant.)

Apparently it's not uncommon for vegans to crave eggs during pregnancy. The forum women assume that it's a craving for protein. They suggest to you eat more tofu scramble with sulfur salt and nutritional yeast. Since I craved eggs during pregnancy (when I was ovo-lacto), I think that it's more than just simply protein. I ate eight eggs a day and couldn't get enough of them. Prior to pregnancy, I didn't eat eggs all that often.

What is it with eggs that would benefit a growing brain and body inside your body?

Arachidonic acid is one of the most abundant fatty acids in the brain, and is present in similar quantities to docosahexaenoic acid (DHA). The two account for approximately 20% of its fatty acid content.[12] Like DHA, neurological health is reliant upon sufficient levels of arachidonic acid. Among other things, arachidonic acid helps to maintain hippocampal cell membrane fluidity.[13] It also helps protect the brain from oxidative stress by activating peroxisome proliferator-activated receptor gamma.[14] ARA also activates syntaxin-3 (STX-3), a protein involved in the growth and repair of neurons.[15] http://en.wikipedia.org/wiki/Arachidonic_acid

Choline. I think this helped the pregnancy induced brain fog that I had. Brain food to the max! You're growing a brain in your womb!

Choline and its metabolites are needed for three main physiological purposes: structural integrity and signaling roles for cell membranes, cholinergic neurotransmission (acetylcholine synthesis), and a major source for methyl groups via its metabolite, trimethylglycine (betaine) which participates in the S-adenosylmethionine (SAMe) synthesis pathways.

Choline deficiency signs
Most common signs of choline deficiencies are fatty liver and hemorrhagic kidney necrosis. Dietary intake of a choline full diet can reduce the severity of the deficiency. A study of this on animals has created some controversy due to the inconsistency in dietary modifying factors.  ^{http://en.wikipedia.org/wiki/Choline}

Cholesterol. This NUTRIENT might be something both you and your baby requires.  This research found a significant correlation between decrease in cholesterol and depressive symptoms postpartum that remained even after adjustment for progesterone concentration. Source.

DHA. Eggs produced by hens fed a diet of greens and insects contain higher levels of n−3 fatty acids than those produced by chickens fed corn or soybeans.[122] In addition to feeding chickens insects and greens, fish oils may be added to their diets to increase the n-3 fatty acid concentrations in eggs.[123]

The addition of flax and canola seeds to the diets of chickens, both good sources of alpha-linolenic acid, increases the omega-3 content of the eggs, predominantly DHA.[124]

The addition of green algae or seaweed to the diets boosts the content of DHA and EPA content, which are the forms of omega-3 approved by the FDA for medical claims. A common consumer complaint is "Omega-3 eggs can sometimes have a fishy taste if the hens are fed marine oils."[125] http://en.wikipedia.org/wiki/Omega-3_fatty_acid#Eggs

So I'm finally watching Vegucated

I like the documentary for entertainment value.

I think T. Colin Campbell would be better off following Fuhrman's recipes, which looked like they were loaded with fat. Fuhrman's patients must be really unhealthy ;-) One recipe was loaded with macadamia nuts. I am getting Fuhrman's book today for the recipes.

A few weeks ago, I blended pre-soaked macadamia nuts, basil, lemon juice, onions, garlic and nutritional yeast and slapped it on top of some quinoa noodles topped with garlic marinara sauce. Holy shit! This was a modified recipe by Alison "Awesome chef" Rivers Samson I found online. She's also created this recipe for macaroni and cheese which uses potatoes, carrots, onions, garlic, cashews, lemon juice, and dijon mustard. Honestly, she's a genius! Next time, I'm going to remove the potatoes and use more nuts.

>>Update. I'm trying to find the recipes in the movie. I don't think they are in his Eat to Live book.

Also regarding T. Colin Campbell, I would like to sneak in about 2 tablespoons of coconut fat into his daily diet along with a drive by squirting of my DHA algae oil into his mouth. Oh, the nastiness I think of!

And Good Lord, Factory Farming is fucked!

My Mother's Experience with Low Dose Nalrexone and Her Glioblastoma IV Brain Cancer

Hopefully the final draft. This is for a UK publication on LDN. I am not a writer!!!


I was diagnosed with a stage four glioblastoma [brain cancer] in February of last year [2011]. After a full course of chemo and radiation, in mid November, I learned about an inexpensive prescription medication, low dose naltrexone. Prior to starting this medication, I was deteriorating. I required a walker and could go only short distances. I had significant memory loss. With all the standard treatment, I was given 10 months to live. The average prediction is 14 months, even after excision, 3.2 cm of tumor remained. After I learned about and obtained a script for low dose naltrexone I gradually regained my ability to walk normally, without a walker, my thinking became clearer. In short, I regained function.

— Laura Arasmo, RN

On the morning of Saturday, 12 February, 2011, my mother, an RN, was working on her nursing notes when she briefly lost consciousness and became disoriented. She dialed 911.

The surgeon excised what he could of a 5.4 cm tumor on Monday, 14 February. Her diagnosis was a grade four Glioblastoma brain tumor (GBM). This is a very aggressive type of brain cancer.

The standard treatment for a GBM involves waiting four to six weeks after surgery and then taking the oral chemo drug, Temodar (temozolomide), for 42 days while undergoing radiation, five days a week for six weeks. Temodar is continued five days a month for six months.

According to the study “MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma” published in the New England Journal of Medicine, about 45% of the 206 patients benefited by using Temodar. It extends life for about five extra months if you have a heritable trait called “silencing of the MGMT/AGT gene”. The median survival is 14 months.

John, our Chinese Medicine practitioner (M.Ac., L.Ac.), is very familiar with GBMs. He urgently wanted my mother to get the MGMT test done on a biopsy of her tumor. I pulled out all the stops to make it happen, despite objections from my mother’s oncologist, who said that Temodar was her only option for treatment at this stage — regardless of whether or not she would benefit. She did not get the test.

John sent a protocol of herbs and vitamins designed to protect mom’s DNA from the damage from chemo and boost her immune system before, during, and after chemotherapy. He also had her remove all sugar and sweets. Cancer cells feed on fructose according to recent research.

Throughout seven months of chemo and radiation, my mother took Dexamethasone, a steroid, to keep the swelling down, and Kepra, to prevent seizures. Every day, I served her smoothies consisting of super green food, Chinese herbs, protein powder, good fats, broad spectrum probiotics, and digestive enzymes. She also took a lot of vitamins and additional herbs. During this time, she didn’t catch any viruses or get thrush.

Near the end of seven months of chemo, mom weaned herself off of Dexamethasone by taking it down a sliver a day. She is extremely sensitive to steroids. She also stopped taking Kepra because she didn’t like the way it made her feel. Her MRIs showed no progression. However, the seven months of chemo had caused negative side effects: her bowels stopped working for a week and she had "chemo brain", a lay term for being very cognitively foggy. In addition, she was frequently nauseous and I could barely get her to eat, drink, or take any pills.

Mom ended her Temodar in September, 2011. She got an MRI in on 3 October. It indicated no progression of the tumor and no new tumors. By the end of October, however, mom was falling apart. She could barely walk, think, or function. Because her tumor is in the left parietal lobe, her right side was affected the most. She said it felt like it belonged to someone else and it was heavy. She refused to take any steroids.

In early November, mom’s health was even worse. She wanted no more standard treatment. Our family started emailing back and forth about beginning hospice care.

I prayed to my beloved spiritual master, Meher Baba (1894-1969), on 8 November 2011, “I can’t do anything and I’m helpless and hopeless. If it is your wish to help her, please do so. I hand her over to you, come what may.” It was a sincere prayer from the core of my being.

The next day, I received a short email forwarded from a friend. The email read that we should check out Low Dose Naltrexone, accompanied by a link to LDNInfo.org. I strongly felt that this was important and called a close family friend who is a retired MD. Being a former ER doctor, he was familiar with Naltrexone as well as other opioid antagonists, but he still had to research it.

Within 9 days after that email, Mom received LDN from Skip’s Pharmacy in Boca Raton, Florida. On 18 November, she started taking a dose of 1.5 mg for two weeks. After two weeks, she raised her dose to 3 mg. Within two or three days of starting the 3 mg dose, she improved DRAMATICALLY. She stopped using her walker and her cognition improved. After two weeks, she raised to a maintenance dose of 4.5 mg each night. She will take this for the rest of her life.

In mid February, Mom had another MRI which showed no progression of her original tumor, but it indicated that a 1.6 cm new tumor had formed outside the surgical bed.

My gut feeling is that this is a tumor that grew from the end of September, when she ended chemo, until Mom started taking the 3 mg dose of LDN. While my “gut feeling” track record is 100%, I also did some research and found that many people report that after chemo it appears that GBMs grow very, very rapidly, tripling in size in just a few weeks.

Mom’s radiation oncologist said that based on her cognitive ability, her physical activity, and other health factors, her MRI didn’t match up with what he was observing. He recommended no treatment and wanted to know more about LDN. He is going to give her another MRI in May. Mom’s main oncologist wanted her to start taking Avastin and was very arrogant about LDN.

Today is the 17th of April, 2012. Mom is very active. She cleans the yard, clips the trees, cleans the house, hauls stuff out of the garage, reads, watches movies, and walks 1.1 miles a day. You would not guess that she has an aggressive brain cancer.

David Gluck, MD stated, “LDN is absolutely unique. And that's part of its problem, in that it's a brand new paradigm, a new way of thinking of treatment. Instead of the medication actually doing the work, LDN goes into the body and essentially tricks the body by forcing it to double and triple its output of endorphins and metenkephalin, also known as opioid growth factor (OGF). Those endorphins and metenkephalin, in turn, cause the immune system to strengthen. A nice way to think about LDN is that it is not like any other medication whatsoever. It is a way to strengthen the immune system.”

I view LDN as a lifeboat with many amenities, but you can add more with nutrition, exercise, and sunshine.

Here’s some of the various nutrients mom takes: Chlorella, Spirulina, Alpha Lipoic Acid, B-complex, multi-vitamins (from whole foods), melatonin, unDenatured whey from pastured dairy cows, high sulforaphane foods like organic broccoli sprouts and organic sprouted kale, N-acetyl-cysteine, CoQ10 (a water and fat soluble kind), Alpha GPC, Phosphatidyl Serine, D3, K1, K2 (MK-7), Mmega 3 DHA/EPA from micro algae, Immucare 1 and Immucare 2, and others.

Mom eats no meat from factory farmed animals/Concentrated Animal Feeding Operations (CAFO). If she eats meat, it’s only from grass/range fed animals. All conventional meat, dairy, and eggs have the number one source of dioxins, according to the EPA.

Mom also consumes a cooked mixture of organic maple syrup and organic bicarbonate of soda. She says this has helped her a lot. I did notice that after a few days of eating this mixture, her fine motor skills improved on her right side. Mom claims this mixture has helped the most, in addition to alkaline foods and drinks. I think mom’s improvement is from the increased levels of Glutathione as well as the health properties of Chlorella and Spirulina from clean, microcystin free sources. I don’t argue with her, perhaps everything is working together.

In closing, I would like to offer a few words of advice based on our experiences: Think for yourself. Research everything. If something doesn’t feel right to you, you will be stressed on some level, which will increase your cortisol. That won’t help your immune system. Listen to your own gut, not someone else’s. Have a neutral attitude, if a positive one is too much of a stretch. Doctors are not omniscient.

Low Taurine and Parkinson's Disease

Amino acids and biogenic amines in cerebrospinal fluid of patients with Parkinson's Disease (PD):
http://www.ncbi.nlm.nih.gov/pubmed?term=12834252

I found this after reading on Beyond Veg that some raw vegan diet guru had Parkinson's like symptoms. I had read a few weeks ago that Taurine was linked to PD. Read the previous post on Taurine too.

Here's something about Taurine and eyesight:

Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells.

http://www.ncbi.nlm.nih.gov/pubmed/22476345

Depression on the vegan diet? Taurine could be one of the reasons...

Depression can be caused by a number of things and diet is one of them. To learn about how low fat/low cholesterol (or no cholesterol) is linked to depression, please read my interview at Let Them Eat Meat. It's not a theory, there's research and everything. Oh goody!

Here's an interesting article about Taurine. Note that taurine activates GABA receptors.

http://www.medicalnewstoday.com/releases/94393.php

Taurine is one of the most plentiful amino acids in the human brain, but neuroscientists are still puzzled by just how brain cells put it to use. Now, a team of researchers at Weill Cornell Medical College in New York City has uncovered a prime site of activity for the molecule, bringing them closer to solving that mystery.

"We have discovered that taurine is a strong activator of what are known as GABA receptors in a regulatory area of the brain called the thalamus," says study senior author Dr. Neil L. Harrison, professor of pharmacology and pharmacology in anesthesiology at Weill Cornell Medical College. "We had discovered these receptors two years ago and showed that they interact with a neurotransmitter called gamma-aminobutyric acid (GABA) -- the brain's key inhibitory transmitter -- that is also involved in brain development. It seems that taurine shares these receptors."

Melatonin and cancer progression (or lack of)

Sharing some stuff regarding cancer prevention that I have in my collection:

For over 15 years the National Cancer Institute at the NIH, Cancer.gov, has known that melatonin is effective against cancer. Why didn't the oncologist share this with us when my mother got brain cancer? Could it be that 20 mg of Melatonin is about $11 a month and Temodar is $200.00 a pill and she got 102 pills? Hummm... Plus Temodar gives doctors repeat business. Mom went to the ER twice because the chemo shut down her bowels.

By the way, apparently marijuana increases melatonin significantly. I have not seen any studies on this, just so-called "common knowledge" stuff on advocates for medical marijuana. Though, they might have a point. I'm in FL, pot is illegal. We had our share of pot smoking in the 70s and 80s and are not fond of weed anymore.

NIH report:

http://www.cancer.gov/cam/attachments/MelatoninSummary.pdf - NIH

In all studies, melatonin was given orally once a day in the dark phase of the photoperiod at doses of 20–40 mg/day. In randomized studies of 1,440 patients with untreatable advanced solid-tumors who received melatonin or supportive care alone, melatonin prolonged survival time and prevented neoplastic cachexia, even though objective tumor regression was seen in only 2% of patients.

http://ukpmc.ac.uk/abstract/MED/3462341/reload=0;jsessionid=IZRO3ncFtCP7mNJYklWM.2

There is some evidence to suggest that the pineal gland influences neoplastic growth. Either crude or partially-purified pineal extracts have been used to treat malignant neoplasms in humans. More compelling evidence indicates that the pineal hormone melatonin, in addition to its well known antireproductive effects, may also exert oncostatic effects particularly in animal models of human breast cancer. However, it is not clear whether melatonin inhibits mammary cancer growth via an indirect neuroendocrine mechanism or via an action directly on the cancer cells themselves. Studies are described in which physiological concentrations of melatonin are shown to have marked inhibitory effects directly on MCF-7 human breast cancer cell growth in culture. Supra- or subphysiological levels of melatonin are completely ineffective in retarding breast cancer cell proliferation. Precursors and metabolites of melatonin such as serotonin, N-acetylserotonin and 6-hydroxymelatonin do not inhibit MCF-7 cell growth. Similarly, neither 5-methoxytryptophol nor 5-methoxytryptamine, regarded by some to be putative pineal hormones, exhibit antimitogenic properties. Melatonin completely blocks the estradiol-induced stimulation of MCF-7 cell proliferation. In defined, serum-free medium, melatonin loses its antimitogenic capabilities unless cells are also simultaneously exposed to either estradiol or prolactin. Therefore, the antiproliferative effect of melatonin may be dependent on the presence of serum and a complex interaction with hormones such as estradiol and/or prolactin.

Effects of the Pineal Hormone Melatonin on the Proliferation and Morphological Characteristics of Human Breast Cancer Cells (MCF-7) in Culture
http://cancerres.aacrjournals.org/content/48/21/6121.short

http://content.karger.com/ProdukteDB/produkte.asp?Aktion=ShowAbstractBuch&ArtikelNr=227533&ProduktNr=245148

The prognosis of brain glioblastoma is still very poor and the median survival time is generally less than 6 months. At present, no chemotherapy has appeared to influence its prognosis. On the other hand, recent advances in brain tumor biology have suggested that brain tumor growth is at least in part under a neuroendocrine control, mainly realized by opioid peptides and pineal substances. On this basis, we evaluated the influence of a concomitant administration of the pineal hormone melatonin (MLT) in patients with glioblastoma treated with radical or adjuvant radiotherapy (RT). The study included 30 patients with glioblastoma, who were randomized to receive RT alone (60 Gy) or RT plus MLT (20 mg/daily orally) until disease progression. Both the survival curve and the percent of survival at 1 year were significantly higher in patients treated with RT plus MLT than in those receiving RT alone (6/14 vs. 1/16). Moreover, RT or steroid therapy-related toxicities were lower in patients concomitantly treated with MLT. This preliminary study suggests that a radioneuroendocrine approach with RT plus the pineal hormone MLT may prolong the survival time and improve the quality of life of patients affected by glioblastoma.

http://www.lef.org/magazine/mag2004/jan2004_report_melatonin_04.htm

http://www.ingentaconnect.com/content/ben/ctmc/2002/00000002/00000002/art00002

http://www.alternative-cancer-care.com/Melatonin_Cancer.html

http://www.townsendletter.com/AugSept2010/estrogen0810.html

Martin Dayton, et al. Defeat Cancer: 15 Doctors of Integrative and Naturopathic Medicine Tell You How. BioMed Publishing Group, May 2011

http://www.naturalnews.com/033511_melatonin_cancer.html

Role of human microflora in health, diet, and disease

Your Gut Bacteria Are What You Eat

http://news.sciencemag.org/sciencenow/2011/09/your-gut-bacteria-are-what-you-e.html

Science, the team reports a similar clustering into enterotypes—although only two of the three showed up clearly—and discovered that dietary habits are linked to the type of bugs that thrive in the gut. People who eat a lot of meat and saturated fat tended to have more Bacteroides in their flora; Ruminococcus prevailed in people who consumed lots of alcohol and polyunsaturated fats, whereas Prevotella favored a diet rich in carbohydrates. It's not clear whether one type of microbial flora is healthier for the host than the other. But if that turns out to be the case, the study offers hope of new ways to improve health by changing diet, Bushman says.

However, other findings reported in the same paper show that you can't change enterotype overnight. The team sequestered 10 volunteers in a hospital and fed half of them a fixed diet very high in fat and low in fiber; the other half of the subjects had the opposite menu. The researchers found that the bacterial populations began to shift within both groups, with some species becoming more common and others less common, but people had the same enterotype when the study ended after 10 days. If switching gut enterotype is possible, the team concludes, it may take a long-term dietary intervention.

Gut Bacteria Reflect Dietary Differences
http://www.usnews.com/science/articles/2010/08/03/gut-bacteria-reflect-dietary-differences

The 'microflora hypothesis' of allergic diseases.
http://www.ncbi.nlm.nih.gov/pubmed/16393316

Role of human microflora in health and disease
http://www.springerlink.com/content/t365180210212606/

What is the Paleo diet for a person with Asian heritage?

Most of India, that is those who are not affluent, eat lentils and rice a lot. My husband just corrected me, he lived in India for 14 years, he said that most of the poor eat millet (bhakri) and vegetables. The Asians in China and Japan, eat rice and noodles as far as I know. Isn't a paleo diet relative to one's ancestors?

When we discuss Paleo eating, are we discussing our common ancestors in Africa? Anybody? I have no idea.

I have noticed with myself that carbs coming from any color veggie except white (with the exception of cauliflower), brown GABA rice, and sprouted lentils have not made any impact my weight. However, anything with sugar, no matter whether it's fruit juice or a vegan cookie, these things do have a negative impact. I also feel sluggish.

Here's an interesting article about microflora and health.
http://www.usnews.com/science/articles/2010/08/03/gut-bacteria-reflect-dietary-differences

Excerpt:

Children from Burkina Faso, who ate millet grain, sorghum wheat, legumes and vegetables, had high numbers of bacteria that digest plant fibers. Also found in the guts of termites [which these children eat], these bacteria break down fibers that humans typically can’t. The bacteria make short-chain fatty acids that give people energy and protect them from inflammatory gut diseases such as Crohn’s disease and inflammatory bowel disorder.

Burkina Faso's children also had decreased numbers of diarrhea-causing bacteria compared with children from Italy. That finding surprised the team, because the African children often drank water polluted with such bacteria.

“The notion that gut flora plays a role in human health has been marginally ignored,” says evolutionary nutritionist Loren Cordain of Colorado State University in Fort Collins, who was not involved with this study. “What we’ve found over the past five or 10 years is that it plays a huge role in our health and well being.”

This is a story, that for me, really drives home that there is no one-size-fits all diet. However, if the microbes and enzymes are in the people, and there's no genetic issue, people can adapt to any diet (sans the sugar, franken food, and factory farming, and GMO crap).

I have a couple theories that will never be proven:

My theory of how early man was able to eat foods with phytic acid and not have it block minerals: our early selves had the phytase enzyme.

My theory of how early man was able to convert ALA from nuts to DHA: healthy levels of the enzyme that does this conversion. Also, no sugar and high levels of Omega 6 to thwart the effort.

The issue is that the same enzymes that convert ALA, also convert LA into its long chain metabolite known as arachidonic acid (AA 20:4ω-6). Given this scenario it is understandable that diets high in omega6 fatty acids can influence, and in reality reduce, the conversion of short chain omega3 fatty acid into its long chain metabolites. http://www.azchia.com/ala_conversion_epa_dpa_dha.htm

You might be aware that a few studies have shown that we convert 0.5% up to 9% - 13%, women doing better than men. I doubt it's estrogen related as some scientists hypothesized. I think it's because women tend to eat healthier than men.

I would love to have the money to check the gut microbes in any healthy long term vegan. It would explain a lot, I think.

It's expensive, I bet. A comprehensive nutritional test my mother had, including her Krebs cycle, was $1400.00. It didn't check her intestinal microbes. All it did was just let us know that she needs more pancreatic enzymes among other things. The MD/ND also told us that we need to rotate our probiotics and change brands every 2 months because we get used certain strains and they are not effective.

Hypertension and sugar! Cinnamon and Curcumin for sugar control

I hope that everyone is becoming aware of the HUGE cholesterol con-job we've all been suffering from. Sugar is implicated in heart disease and it plays a big role in hypertension too.

Without having any scientific proof, I have no problem with this statement:

When a food is good for you, it’s not just good for your heart, it's good for your entire body.

When a food is bad for you, it's bad all over.

Sugar is bad on your figure, brain, heart, and every organ including the largest: your skin.



Sugar-sweetened beverages and hypertension.
http://www.ncbi.nlm.nih.gov/pubmed/21142633

Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease1,2,3
Cancer cells slurp up fructose, US study finds
http://www.ajcn.org/content/86/4/899.abstract

Sugar, not just salt, linked to high blood pressure
http://www.cnn.com/2010/HEALTH/07/01/glucose.blood.pressure/index.html

Patterns: Added Sugar and High Blood Pressure
http://www.nytimes.com/2010/07/06/health/research/06patterns.html

There's very, very few studies on how beneficial cinnamon and curcumin are for controlling blood sugar. The lack of studies doesn't represent that they're not effective.

My belief is, based simply on profit and loss, is that the lack of many studies on ANY un-patentable natural substance is an indicator that it has the potential of being very effective.

Improved Insulin Resistance and Lipid Metabolism by Cinnamon Extract through Activation of Peroxisome Proliferator-Activated Receptors
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602825/

Cinnamon Improves Glucose and Lipids of People With Type 2 Diabetes
http://care.diabetesjournals.org/content/26/12/3215.full

Turmeric
http://www.umm.edu/altmed/articles/turmeric-000277.htm

Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice.
http://www.ncbi.nlm.nih.gov/pubmed/18398869

Curcumin inhibits glucose production in isolated mice hepatocytes.
http://www.ncbi.nlm.nih.gov/pubmed/18221818

Cancer cells slurp up fructose, US study finds and some interesting studies regarding cancer and pH

Here's the link on fructose causing cancer cells to go wild. What? Only one. Yes, only one. We're lucky to get one.

http://www.reuters.com/article/2010/08/02/cancer-fructose-idAFN0210830520100802

If you have a mother who has cancer with only a 1% chance of survival, there's nowhere else to go but way out of the box. There you can run across some pretty nutty things, but inside the box is chemo, radiation, and arrogance. Then hospice. Thankfully, I was out of the vegan box before she was diagnosed.

In the course of reading a lot of holistic health books, blogs, and forums to find something to help my mother, sugar came up a lot.

"Sugar feeds cancer" I saw it everywhere.

Now, what the hell do you eat for fun? Freeze some berries and bananas (just not 30 of them!) and blend. Add some coconut meat or an avocado and lemon juice. That's one idea. You can get very clever, just don't juice your fruit. Eat the fruit blended so you still have the fiber to slow down the impact on your blood sugar.

Here's an alternative health web site and excerpt:
http://www.nutritioncancer.com/sugarfeedscancer.html

SLOW CANCER GROWTH BY LOWERING BLOOD AND GUT GLUCOSE

(This is old, it's fructose not glucose -- see the Krebs cycle section on the Sugar: The Bitter Truth video on YouTube).

"Cancer cells demonstrate a 3 to 5 fold increase in glucose uptake compared to healthy cells."
Demetrakopoulos, GE, Cancer Research, vol.42, p.756S, Feb.1982

“Sugar is the most hazardous foodstuff in the American diet.”
Linus Pauling, PhD, twice Nobel laureate

WHAT'S AHEAD?
Cancer cells feed almost exclusively on sugar. You can slow tumor growth by:
> eating a diet that lowers blood and gut sugar
> exercise to burn up any extra glucose in the blood
> taking supplements such as chromium, CLA, and gymnema
> using medications, if necessary, for better control of diabetes

A moth is attracted to bright light, which can be its own demise if the bright light is a flame. Americans consume 140 pounds of refined sugar per year, mostly in the form of sucrose (white sugar) and corn syrup. Our incidence of obesity, diabetes, and many cancers has escalated parallel to our rise in sugar intake. We consume 15 billion gallons of soft drinks, 2.7 billion Krispy Cremes, and 500 million Twinkies per year. Our appetite for sugar is like a hummingbird sucking on sweet food all day long.

Sugar Feeds Cancer: A simple saying for something more complex.
http://www.healingdaily.com/detoxification-diet/sugar.htm

German Otto Warburg, Ph.D., the 1931 Nobel laureate in medicine, first discovered that cancer cells have a fundamentally different energy metabolism compared to healthy cells.

The gist of his Nobel thesis was this: malignant tumors frequently exhibit an increase in "anaerobic glycolysis" - a process whereby glucose is used by cancer cells as a fuel with lactic acid as an anaerobic by-product - compared to normal tissues.(1)

The large amount of lactic acid produced by this fermentation of glucose from the cancer cells is then transported to the liver. This conversion of glucose to lactate creates a lower, more acidic PH in cancerous tissues as well as overall physical fatigue from lactic acid build-up.(2,3) Therefore, larger tumors tend to exhibit a more acidic PH.(4)

Cancer and Alkaline pH studies

Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
http://www.ncbi.nlm.nih.gov/pubmed/19276390

Acid pH in Tumors and Its Potential for Therapeutic Exploitation
http://cancerres.aacrjournals.org/content/49/16/4373

Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
http://mct.aacrjournals.org/content/5/5/1275.abstract

Recent progress in tumor pH targeting nanotechnology.
http://www.ncbi.nlm.nih.gov/pubmed/18571265

Sodium Bicarbonate Appears To Slow Progression Of Chronic Kidney Disease
http://www.medicalnewstoday.com/releases/157902.php

"Chronic kidney disease (CKD) and cancer are connected in a number of ways in both directions: cancer can cause CKD either directly or indirectly through the adverse effects of therapies; CKD may, conversely, be a risk factor for cancer; and both may be associated because they share common risk factors, often"

http://scholar.google.com/scholar?hl=en&lr=&q=related:CFfJPxxsgRsJ:scholar.google.com/&um=1&ie=UTF-8&ei=LTZmT8vgKMuMsALXxqC3Dw&sa=X&oi=science_links&ct=sl-related&resnum=6&ved=0CKcBEM8CMAU

Brainwashed

If you've been keeping up on the news, we've now learned that sugar is behind heart disease and possibly other chronic diseases (like cancer*). I wrote this a couple years ago on a blog post thread on this site:

Actually, I hope in the near future, it will be found that sugar causes heart disease and, most especially, high fructose corn syrup. But for now, everyone can be brainwashed.

I removed my original typo.

*I don't need proof. I'm certain. I'll post a study the effects of fructose, not glucose on cancer cells once I locate it again.

Here's what I send to all people, healthy and sick. This information is vital to improve your life

This is some videos and links I've gathered over the last year or two. I add more when I find something that really stands out. I share these far and wide in emails, on my facebook pages that I admin, and now with you. It's up to you to think for yourself and determine whether or not these are helpful.

Here's a statement that should be obvious, but many people simply don't make the connection:

Nutrition is not created in isolation. When you, for example, consume DHA (I get mine from micro algae) and the bottle says "Good for Brain Health", do you think your brain is separated from your vascular system? It is not. Your entire body is improved when you start adding good nutrition and you remove sugar. Sugar is fucked. Thanks for listening.

How Diet Lifestyle Helped Dr. David Servan-Schreiber, MD, Phd live 20 more productive years after brain cancer diagnosis.
http://www.youtube.com/watch?v=XaDt3AJQ98c&feature=share

Glutathione: The "mother" of all antioxidants...
http://www.youtube.com/watch?v=Eh2PYQBICWs

Sugar: The Bitter Truth
What is responsible for heart disease? Sugar.
http://www.youtube.com/watch?v=dBnniua6-oM

How Diet Cured Dr. Terry Wahls of MS
http://www.youtube.com/watch?v=KLjgBLwH3Wc

How Coconut Oil Dramatically Helped Dr. Mary Newport's husband with Alzheimer's Disease
http://www.tampabay.com/news/aging/article879333.ece

Super-Sticky 'Ultra-Bad' Cholesterol Revealed in People at High Risk of Heart Disease
http://www.sciencedaily.com/releases/2011/05/110526204953.htm

Is sugar toxic 60 minutes 1 April 2012 -
http://www.youtube.com/watch?v=pxG3YiBMMZE

How Stress Influences Disease: Study Reveals Inflammation as the Culprit

A research team led by Carnegie Mellon University's Sheldon Cohen has found that chronic psychological stress is associated with the body losing its ability to regulate the inflammatory response. Published in the Proceedings of the National Academy of Sciences, the research shows for the first time that the effects of psychological stress on the body's ability to regulate inflammation can promote the development and progression of disease.

http://www.sciencedaily.com/releases/2012/04/120402162546.htm

Chlorella's immune system benefits!

I hope that people go through some kind of common sense generator so that they understand the following:

Nutrition is not patentable and it's not profitable. There is barely any research on how good something like Chlorella (when it's from a clean source - see previous post) can be. My mother's current, rocking status from a deadly brain tumor is due to Low Dose Naltrexone (all but written off by mainstream medicine) and good nutrition. She walks 1.1 miles a day, cleans, cooks, and generally is in everyone's business, just like old times!

Here's some of the research I've found on Chlorella or Chlorophylls. Note: Improved immune system is improved thinking, skin, circulation, the whole enchilada (hold the cheese). Alright:

Some studies might be repeats:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613958/
Chlorella vulgaris triggers apoptosis in hepatocarcinogenesis-induced rats:
We evaluated the effect of CV on apoptotic regulator protein expression in liver cancer-induced rats.

Apoptosis is programmed cell death as in the fast dividing cells in cancer.

http://lpi.oregonstate.edu/infocenter/phytochemicals/chlorophylls/

The scientific and anecdotal information available suggests that broken cell wall preparations and extracts of Chlorella pyrenoidosa in the diet provides important nutrients necessary to maintain good health, resist infection, and restore immune functions in immunocompromised patients.
http://onlinelibrary.wiley.com/doi/10.1002/ptr.2650040605/abstract

A review of recent clinical trials of the nutritional supplement Chlorella pyrenoidosa in the treatment of fibromyalgia, hypertension, and ulcerative colitis.
http://www.ncbi.nlm.nih.gov/pubmed/11347287

Chlorella (Chlorella pyrenoidosa) supplementation decreases dioxin and increases immunoglobulin a concentrations in breast milk.
http://www.ncbi.nlm.nih.gov/pubmed/17472477 & http://online.liebertpub.com/doi/abs/10.1089/jmf.2006.023

Oral administration of Chlorella vulgaris augments concomitant antitumor immunity.
http://www.ncbi.nlm.nih.gov/pubmed/2229925

Chlorella vulgaris administration prevents HgCl2-caused oxidative stress and cellular damage in the kidney
http://www.springerlink.com/content/aj330507x7881704/

Effect of chlorella and its fractions on blood pressure, cerebral stroke lesions, and life-span in stroke-prone spontaneously hypertensive rats.
http://www.ncbi.nlm.nih.gov/pubmed/17330510

Antitumor effect induced by a hot water extract of Chlorella vulgaris (CE): resistance to Meth-A tumor growth mediated by CE-induced polymorphonuclear leukocytes.
http://www.ncbi.nlm.nih.gov/pubmed/3845850

Immunomodulation by a unicellular green algae (Chlorella pyrenoidosa) in tumor-bearing mice.
http://www.ncbi.nlm.nih.gov/pubmed/3253484


The information below is copied from excerpts from various books. It was gathered by stealing the bottom half of the Chlorella post on Natural News. (Whatever that guy says at Natural News needs to be researched because some of the things he says are a bit whacked.) But even if a guy who claims to be Santa Claus gives you good advice, do you ignore it? Discern, discriminate, and think for yourself!

Chlorella is green algae, which, in a study by Fukada, was observed to have immune-stimulating qualities. It's another herb whose healing properties have not been of much interest to Western medicine.
Aids A Second Opinion by Gary Null PhD with James Feast, page 528

Most research has been done on a one-celled alga known as chlorella. This has been shown to have powerful anti-tumor effects. An oral administration of chlorella protected between 73 and 80 percent of mice against several kinds of cancer. However, all the mice that received chlorella that had been deprived of its protein, died.
Cancer Therapy by Ralph W Moss PhD, page 203

Chlorella can neutralize and eliminate some of the contaminating heavy metals and strengthen the immune system, and GLA, which enhances prostaglandin production and possesses anti-inflammatory abilities.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 135

Japanese scientists studied chlorella (pyrenoidosa) as a biological response modifier. First, experimental mice were given chlorella every other day for ten days. Then one of three kinds of cancer—breast, leukemia or Ehrlich ascites—were injected into them. All of the untreated mice died within 20 days. But over 70 percent of the treated ani-
Cancer Therapy by Ralph W Moss PhD, page 203

Natural healers recommend chlorella for nonspecific complaints such as fatigue and for anyone who generally wants to feel stronger or healthier. It is also used by alternative physicians as part of an overall cancer treatment program.
Earl Mindell's Supplement Bible by Earl Mindell RPh PhD, page 24

Since chlorella does not directly kill cancer cells, the scientists concluded that its effects were caused by boosting the immune response.
Cancer Therapy by Ralph W Moss PhD, page 204

Chlorella does not contain the biliprotein phycocyanin found in blue-green algae such as spirulina and wild blue-green; therefore it does not have this anti-cancer dimension. Those who benefit from the immune-strengthening value of CGF and also want phycocyanin can simply add a blue-green alga. Any two or more micro-algae combine well, especially if both are needed.
Healing With Whole Foods by Paul Pitchford, page 194

In another experiment, a group of scientists took a hot water extract of chlorella and injected it into the body cavities of mice that had first been inoculated with tumor cells. They found that "survival times were strikingly prolonged." Furthermore, when they gave mice injections of chlorella, their cells still exhibited "an anti-tumor effect" 24 hours later. This effect remained intact even after 'T' type white blood cells and macrophage (scavenger) cells were destroyed, but it was effectively wiped out by irradiation. Chlorella's anticancer effect was thus dependent on the portion of the immune system most sensitive to x-rays.
Cancer Therapy by Ralph W Moss PhD, page 204

Many reports have come from Japanese research studies that followed the nuclear catastrophe resulting from atomic bombs that were dropped on the cities of Hiroshima and Nagasaki in 1945. In a report to the General Meeting of the Pharmaceutical Society of Japan on an early study in animals, Ichimura (1973) reported that chlorella (8 grams daily) increased elimination of cadmium: threefold in feces and sevenfold in urine. Other researchers from Japan showed that chlorella helped detoxify uranium and lead (Horikoshi et al. 1979). chlorella has detoxification potential for similar compounds, such as dioxin and polychlorinated biphenyls. (PCBs are chemical compounds used in plastics, insulation, and flame retardants, with potential to cause cancer and liver damage.) Other research indicates that chlorella is useful in detoxification of high levels of mercury in the body caused by removal of mercury amalgam. Some dentists recommend chlorella to patients who are having mercury amalgams replaced (as well as to themselves and staff who can incur accidental exposure from day-to-day exposure to amalgam filling procedures) (O'Brien 2001).
Disease Prevention And Treatment by Life Extension Foundation, page 859

Japanese researchers recently discovered that chlorella could raise blood levels of the protein albumin. Albumin is one of the body's most powerful antioxidants as well as its main transport system, carrying vitamins, minerals, fatty acids, hormones, and other essential substances throughout the body. Albumin is also instrumental in carrying toxins away from cells and into the liver, where they are broken down and later excreted from the body. Without adequate levels of albumin, the kidneys, liver, and other vital organs cannot do their jobs as well, and the immune system cannot function as efficiently. Numerous studies have documented that a low albumin level is a marker for serious illnesses such as cancer and heart disease. They point to test-tube studies confirming that raising albumin levels can both prevent cancerous changes and extend the life span of human cells. Although no such studies have been done on humans, it makes sense that raising albumin levels would help to restore health.
Earl Mindell's Supplement Bible by Earl Mindell RPh PhD, page 24

The law of similars ("like cures like") offers another approach to understanding the immune-strengthening quality of chlorella: an organism with a tough outer cell wall may well possess the basic properties which strengthen our own cellular structure against invading organisms and toxins.
Healing With Whole Foods by Paul Pitchford, page 193

Since chlorella has a true nucleus, it is a more evolved organism than the other common green micro-algae and therefore may offer superior-quality RNA/DNA. This particular aspect of its RNA/DNA, measured by the CGF, strengthens immunity by improving the activity of T- and B-cells, which defend against viruses and other invading microorganisms, and macrophages, which destroy cancer and cellular debris in general.
Healing With Whole Foods by Paul Pitchford, page 194

For cancer, AIDS, Epstein-Barr syndrome, multiple sclerosis, rheumatoid arthritis, tumors, Candida overgrowth, excessive mucus, edema, and other conditions associated with dampness, wild blue-green is generally the most useful. Individuals who are not particularly excessive will benefit from a moderate dosage of 1.5-2 grams. The upper dosage ranges of cereal grass, chlorella (excellent for disorders with immune malfunction), spirulina, and dunaliella are also beneficial additions (often spirulina and dunaliella are used together). One may choose the one or two most appropriate of these green foods based on their properties.
Healing With Whole Foods by Paul Pitchford, page 204

Chlorella helps protect the body in its fight against both viruses and cancer. A series of studies during the 1980s showed that tumor growth in mice could be reduced or stopped by injecting a water solution of chlorella…
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 231

This research, says Tim Sara, president of Nature's Balance, a major U.S. supplier of chlorella, "has confirmed that serum levels of albumin are extremely accurate indicators of overall health status and that low albumin levels exist at the onset and progression of virtually every nonhereditary, degenerative disease process, including cancers and cardiovascular heart disease." A series of studies with rats demonstrated that chlorella supplementation increases albumin levels by 16% to 21%.
Heart Disease by Burton Goldberg, page 131

Some micro-algae have very favorable nutritional profiles for cancer and immune therapies. Spirulina, chlorella, and wild blue-green (Aphanizomenon flos-aquae) provide cellular protection with exceptional amounts of beta carotene (provitamin A) and chlorophyll; dunaliella is the highest known natural source of beta carotene. chlorella, the alga to emphasize in those with the greatest deficiency, stimulates immunity in the treatment of all degenerative diseases by means of the "chlorella Growth Factor" (CGF). These bitter micro-algae often work well with chlorella or spirulina.
Healing With Whole Foods by Paul Pitchford, page 378

Chlorella is a one-cell blue-green alga that is highly nutritive as a food and also stimulates the immune system. It increases macrophage activity and has shown antitumor effects. Chorellan is a substance found in chlorella that stimulates interferon production. There are several papers on the prevention and/or inhibition of cancer using chlorella as well as documentation of its DNA repair mechanism.24 one of the many benefits of chlorella is its ability to increase serum albumin levels. A drop in albumin level has many negative effects on the body. Of all the super green foods, chlorella is the one that impresses me the most.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 71

A study on chlorella published in Japan in 1992 showed that chlorella has impressive effects on blood chemistry. It increased red blood cells, white blood cells, platelets, and albumin. The ability of chlorella to increase albumin is vitally important because so many people with cancer have a decreased level of albumin. This decreased level correlates with a poor prognosis; chlorella is a truly important supplement for anyone whose albumin level is low.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 232

Chlorella is useful in a wide variety of maladies and conditions, including chronic gastritis, high blood pressure, some forms of cancer, diabetes, constipation, anemia, and high cholesterol. It helps clear toxic metals from the body. Chlorella has antitumor and anti-inflammatory properties and strengthens the immune system. The microalgae support normal growth and help maintain health in old age. They reduce pitta and kapha and, in moderation, are healing for vata.
New Whole Foods Encyclopedia by Rebecca Wood, page 81

There have been dozens of animal studies on chlorella and chlorella extracts involving immune response to cancer. One such study involved mice given chlorella prior to transplantation of mammary carcinoma. The results were a 70 percent sixty-day survival of the chlorella group versus no survival in the control group. Mice in the control group were also transplanted with tumors but did not receive chlorella.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 232

Green foods refers to chlorophyll-rich supplements from sources such as microalgae (including spirulina, blue-green algae, and chlorella) and the young grasses of cereal plants (particularly barley, wheat, and alfalfa). Chlorophyll acts as an antioxidant and may have medicinal benefits against cancer and immune problems. Many people also take green-food concentrates to boost energy levels and physical and mental performance.
Off The Shelf Natural Health How To Use Herbs And Nutrients To Stay Well By Mark Mayell, page 291

In 1990, a study on chlorella was performed at the Medical College of Virginia. Fifteen glioblastoma patients were administered 20 grams of powdered chlorella and 150 ml of liquid chlorella, in some cases combined with standard chemotherapy and/or radiation therapy. There was a significant increase in health and immune status immediately, and a striking 40 percent two-year survival rate was reflected in follow-up studies. This is extremely rare for this type of tumor, which normally might yield a 10 percent survival rate after two years.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 232

There are other beneficial algaes, such as spirulina, a blue-green alga, and other super green foods, but I believe chlorella is the best, particularly for people with cancer and/or a weak constitution.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 232

Lactoferrin, lipoic acid, and chlorella are the three best supplements I have found for enhancing the nutritional status and raising the albumin level of those with cancer or any chronic illness. Lactoferrin, an iron-binding protein, is a vital element to the human body. It retrieves iron from the foods we eat and delivers it to areas of the body where it is needed. Many people, particularly those with cancer, become anemic because their body is not assimilating iron properly.
Herbal Medicine Healing Cancer by Donald R Yance Jr, page 238

Green-food concentrates are chlorophyll-rich supplements. Most are derived from microalgae (such as spirulina, blue-green algae, or chlorella) or from the young grasses of cereal plants (such as barley, wheat, and alfalfa). Chlorophyll acts as an antioxidant and may have medicinal benefits against cancer and immune problems
Off The Shelf Natural Health How To Use Herbs And Nutrients To Stay Well By Mark Mayell, page 229

A chlorella extract has demonstrated antitumor and antime-tastatic effects in animal experiments. Chlorella has shown some experimental antiatherogenic activity and some radio-protective and chemo-detoxifying effects. It has shown some preliminary benefit in immune function and in some with fibromyalgia.
PDR For Nutritional Supplements by Sheldon Saul Hendle and David Rorvik, page 89

Chlorella. A freshwater single-celled green algae consisting of 60 percent protein, high levels of chlorophyll and vitamin A, and dozens of other nutrients. It's being researched as both an antiaging supplement and a cancer preventive.
Power Aging by Gary Null, page 149

Additional beneficial foods are chlorella and pearl barley. These foods contain germanium, a trace element beneficial for the immune system. It is also a good idea to include kelp in your diet in the form of giant red kelp…
Prescription For Dietary Wellness by Phyllis A Balch, page 10

I also recommend the use of chlorella and/or Green Magma as a twice-daily green drink. Chlorella is a highly nutritive one-celled blue-green algae that is a powerful immune system stimulant that has also demonstrated anti-tumor effects. Research has shown that chlorella is able to repair the DNA system and increase serum albumin levels.
Treating Cancer With Herbs by Michael Tierra ND, page 304

Chlorella is a tiny single-celled water-grown green alga that contains the highest chlorophyll level per ounce of any plant, as well as protein (nearly 58 percent), carbohydrates, all of the B vitamins, vitamins C and E, amino acids (including all nine essential ones), enzymes, and rare trace minerals. Chlorella strengthens the immune system.
Prescription For Dietary Wellness by Phyllis A Balch, page 33 72

I also recommend the use of chlorella, which is a highly nutritive one-cell blue-green algae that is a powerful immune system stimulant that also has demonstrated anti-tumor effects. Research has shown that chlorella is able to repair DNA and increase serum albumin levels.
The Way Of Herbs by Michael Tierra, page 309

Green chlorophyll is the main coloring matter in all green plants, and it relates most closely to Qi, the life force. Green plants and algae are high in chlorophyll, include spirulina and chlorella. Foods and herbs that contain high levels of chlorophyll show pharmacological evidence of cancer prevention, perhaps because pigments in green vegetables such as spinach, kale, broccoli, and lettuce bind with and thus stimulate excretion of cancer-causing chemicals. Even more interesting is a report from one researcher that "Given their exclusive dietary origin, . . . chlorophyll metabolites may represent essential nutrients that coordinate cellular metabolism (through nuclear receptors)."
The One Earth Herbal Sourcebook by Alan Keith Tillotson, page 84

Chlorella: 1 to 2 teaspoons two or more times daily. Dense and nutrient rich in vitamins, minerals and easily assimilable protein, it supports the immune system of patients undergoing chemo and radiation therapy, increases phagocytes, T-cells and cancer killing B cells.
Treating Cancer With Herbs by Michael Tierra ND, page 268

In all anticancer diets, one should incorporate chlorophyll-rich foods derived from the juice of wheat grass, barley grass or a special green algae known in the trade as chlorella. Chlorella, has been found to have greater anticancer properties than any other anticancer supplement. Of course, these 'green foods' are very rich in a wide variety of vitamins, minerals and other health-giving constituents as well.
Treating Cancer With Herbs by Michael Tierra ND, page 309

I recommend chlorella to all cancer patients regardless of any other green drink they might use. Chlorella is a small, one-celled algae containing a nucleus and a large amount of chlorophyll. Its protein content is approximately 58% with the balance made up of carbohydrates, all the B Vitamins, Vitamin C and E, amino acids and valuable trace minerals. It has more B12 than liver and a substantial amount of beta-carotene. Because it has a strong cell wall, it requires processing in order to make all of its nutrients available. It is virtually a complete food in itself. It acts as both a powerful nutrient and a detoxifying food.
Treating Cancer With Herbs by Michael Tierra ND, page 361

My vegan girlfriend had restless leg syndrome until she tried this

A while back, I started giving Mom spirulina sourced from a clean, biosecure company in Hawaii. It's been very, very helpful for her health. More recently I added chlorella. Bam! I'll post some excellent studies on the health benefits of both, such as increasing your own naturally killer cells to kick cancer's ass, once I put them together.

It's vital that you get your algae from a very reputable source to make sure there's no microcystins in it. That is a toxin. The word "microcystins" looks similar to the word "microcystis". They are not the same. There can be -- if your algae comes from a lousy source -- microcystins in the microcystis. Cyanobacteria, microcystis, and blue-green algae are the same thing. I say this because I got into a heated email thread argument with someone who was just not getting it. She was sick, but she was also severely nuts. At the end of the thread I mentioned something about the differences between heme iron and non-heme iron, the latter is found in spirulina. She replied that the RDA for iron is so that people don't get scurvy. Oh God, how I wanted to run around the block to shake off that experience. Scurvy is from a lack of vitamin C. Anyway, for my own sanity, I unsubscribed from all health forums. Fuck it.

Now that I've vented, let's get back on subject. Today I am going to mention that spirulina and ChlorEssence brand Chlorella (I dig that brand a lot) are very good to try for restless leg syndrome. My vegan girl friend, the one who gave me the Vegan Outreach booklet and lent me the Peaceable Kingdom video 8 years ago, has had a very hard time with restless leg syndrome. She shakes all night. Anyway, she recently called me and I mentioned magnesium regarding her restless leg. She uses it. I don't recall researching restless leg syndrome, but I thought it might be related to magnesium deficiency based on something I read. I have too much stuff in my brain. Then she said that she has very low dopamine and that has something to do with her problem.

Hey! I've been secretly researching how to increase dopamine for about 2 years now. Here's why: when you are in love, your dopamine levels are high. When I was courting my husband, yes it was me courting him at first (now he's paying me back), we were in a long distance relationship 3,000 miles apart. I never felt better, though. This lasted nearly 2 years and I appreciated it because I had this dopamine coursing through me. I was motivated all the time to work out, make a lot of money, and all sorts of great things. Once that wore off, I've been looking for it ever since. And I found it! Motivation in a food: ChlorEssence or Spirulina.

So I mentioned that she should try ChlorEssence or Spirulina for her restless leg, because both contain nice levels of tyrosine. Tyrosine is the precursor to dopamine. Well that's the short version, there's more to it than that, which you can look up yourself. I had no idea that restless leg was both dopamine and iron related, but apparently it is. Long story shortened: she's sleeping like a baby!


I'm so happy!

This is excerpted from somewhere, I can't find the source: Tyrosine is a nonessential amino acid the body makes from another amino acid called phenylalanine. It is a building block for several important brain chemicals called neurotransmitters, including epinephrine, norepinephrine, and dopamine. Neurotransmitters help nerve cells communicate and influence mood. Tyrosine also helps produce melanin, the pigment responsible for hair and skin color. It helps in the function of organs responsible for making and regulating hormones, including the adrenal, thyroid, and pituitary glands. It is involved in the structure of almost every protein in the body.

I use the Sequel Naturals brand ChlorEssence. This is grown in their own fresh water (not ocean water) and tested every month. Canada has stricter rules than the US. There are no microcystins (toxins) and no iodine because it's not sea water. ALWAYS CHECK YOUR SOURCE because many of the brands are contaminated. ChlorEssence is the BEST, no shit. It has the highest level of CGF.

Both spirulina and chlorella have the amino phenylalanine. Do not eat it if you have Phenylketonuria.

Apparently, chlorella has highest amount of tyrosine in all foods, next to spirulina, including meat. This needs to be confirmed as I could only find spirulina in the nutritional database.

It's FAR better, safer in my opinion, to eat a food like spirulina or ChlorEssence than consume powdered tyrosine. I eat both spirulina and ChlorEssence every day and I also have several sacha inchi seeds. All three have good levels of many, many amino acids and really good levels of tyrosine.

Read more: http://www.umm.edu/altmed/articles/tyrosine-000329.htm#ixzz1qYSpkiWc

My interview on LetThemEatMeat.com

I've am featured on LetThemEatMeat.com - an ex-vegan blog by someone I consider a good friend now. Here's the interview:

http://letthemeatmeat.com/post/20896431565/quasivegans-christina-arasmo-beymer-discusses-her

Vitamin D and questionable recommendations from the IOM

Vitamin D report thanking the Vitamin D experts who didn't get their feedback either published in the report or anywhere else.
http://books.nap.edu/openbook.php?record_id=13050&page=R7
http://books.nap.edu/openbook.php?record_id=13050&page=R8

Regarding the feedback not being included, from the IOM / FNB: Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the conclusions or recommendations nor did they see the final draft of the report before its release.

http://www.vitamindcouncil.org/news-archive/2010/vitamin-d-council-statement-on-fnb-vitamin-d-report/
http://www.anh-usa.org/action-alert-is-the-institute-of-medicine-in-bed-with-big-pharma/

Glenville Jones, PhD and his conflict of interest:
http://www.nature.com/nm/journal/v17/n1/full/nm0111-9.html
http://jco.ascopubs.org/content/25/6/669
http://www.cytochroma.com/news/data_presentations.html

Sunshine can't be patented and neither can D3.

How to make sprouted brown rice (GABA)

Here's how to do it:

http://www.instructables.com/id/HOWTO-make-GBR-germinated-or-sprouted-brown-rice/

This stuff is the GABA rice and it's super tasty. It's also super expensive if you don't make it yourself. The nutrient density is seriously improved compared to regular brown rice. I literally can eat it alone, it's so good. My husband swore that it had some spices added to it to make it yummy.

I don't have the numbers but the increase in amino acids and ions is a lot.
http://en.wikipedia.org/wiki/GABA_receptor

Here's some more information on it:
http://www.foodrecap.net/guide/gaba-rice/

www.jbmb.or.kr/jbmb/jbmb_files/[36-3]0305281541_319-325.pdf

"The effects of germination and germination conditions on the
concentrations of GABA, Glu, GAD and soluble calcium ions
were evaluated in brown rice. Germination resulted in
significant increases in the GABA concentrations that could
be further increased by additions to the soaking solution that
was used for the germination; the highest GABA
concentrations were obtained by germination with the
chitosan/glutamic acid (CG) solution. The CG-germinated
brown rice also appeared to have higher GAD levels when
compared to the non-germinated and water germinated brown
rice. The concentration of calcium ions was also higher in the
CG-germinated brown rice than in the non-germinated brown
rice. In contrast, the highest Glu concentrations were found in
the non-germinated brown rice; the Glu levels were very low
in the germinated brown rice. Overall, the data clearly show
that the concentrations of GABA, GAD, and soluble calcium
are significantly increased by germination of the brown rice,
with the greatest increase in the CG-germinated brown rice,
while Glu is highest in the non-germinated brown rice.
Previously, we demonstrated that the germination of brown"


Please also google sprouting almonds and beans.

The Mission of this Site

As you might be aware, my mother got diagnosed with one of the deadliest forms of brain cancer early last year. I moved back to Florida just 10 months after moving to California from Florida. My mother was a mess and I was a mess in a different way. We're both so much better now. (My better status doesn't mean that I have much time to delete or modify the old stuff, which might be pathetic content wise. I noticed a few errors that are cringe worthy.)

Finding about ex-vegans gave me a healthy dose of skepticism and critical thinking in general. This has proved very helpful. If I was to heed the advice of conventional, Western medicine, which is not based on nutrition, or ignore out-of-patent, generic, and more effective drugs that work better with less side effects, my mother would be either dead or severely debilitated. She is neither. Yay Mom!

Yay to Rhys Southan whose ex-vegan story began my hobby in nutrition. My mother is alive and kicking today partially because of this hobby. Personally, I feel that it is God Who guided me inwardly from the very beginning. Others might call it the law of attraction or just plain luck. No matter: I am grateful to whatever the-great-thing-that-transpired-in-my-life is called that sent me in this direction.


Original Intent of this site on 12/6/10 at 5:17 pm Pacific Time:

The mission of this site is to present the reasons why there are ex-vegans from a nutritional standpoint. However, sometimes I write from a psychological and/or spiritual perspective because it's really intertwined with the diet for many people.

I may be way off on the deep end or I may have some insight, that's for you to determine for yourself. I was very much shaken and sad to realize that my most beloved diet was not perfect for everyone. I had to address the question: If this is the "One Diet to Rule Them All" then there shouldn't be any ex-vegans?

But there is no diet like that. And there are ex-vegans.

What I want is a place, a resource, where a vegan who is groggy, has nose bleeds, cavities, hair loss, low libido, and so forth can turn to to get some ideas in regular everyday language. Such as: Groggy, foggy, can't concentrate? Check this out vegan dude... Simple ones such as natural mineral salt with the natural iodine, kelp, using oil in your kale salad, cooking your carrots, and other ideas like that. Getting healthy and feeling healthy may come down to something simple. It is that way in coding many times.

People feeling sick or tired need to know that they are not alone and they need a safe place to come to without being lambasted for failing or feeling bad on the most "precious" (using another LOTR term) diet. People who are thriving on the vegan diet sometimes take it as a personal affront if everyone is not thriving on it. Well, sorry to say, once again, "We are not clones of Donald Watson". Yeah, I'm sick of hearing it too.

I am not an expert. No one is an expert if you equate being an expert with some kind of omniscience. You need to discern and determine all aspects of your life and the questions and problems before you. If you want sound vegan nutrition advice, go to VeganHealth.org and JackNorrisRD.com. Why is he better than an MD like Dr. MacDougall? Because he has no monetary gain or reputation (God like status) to protect and his motivations are freaking awesome, that's why! If you are a heart patient, go to a doctor.

Use this site at your own risk. Be mad at me if you want. When I have time in January, I will fix this site up and clean up the writing, or trade with a writer. I'm not a writer, I'm an artist.

Vitamin D and African Americans

Because of my mother's brain cancer, I have this keen interest in nutrition for curing, healing, or alleviating suffering in cancer. Whatever I can get, you know?

You wouldn't believe how well Mom is doing! She keeps herself alkaline which she claims has helped her a lot. I noticed a big improvement in cognition and fine motor skills. My personal jury is still mulling over the alkaline diet and its potential. But, hey it's healthy plant food, so I have no problem with the food. I've increased her precursors to glutathione (lots of broccoli sprouts and N.A.C. -- watch it now, not too much or vomiting might ensue). She's really doing a lot better. Now she's cleaning the house!

I hear from people, through the forums I belong to and the facebook page that I admin on Low Dose Naltrexone, that their doctors are recommending mega doses of vitamin D for chronic disease. I saw this for myself with my mother's Neuro. These doctors just read the headlines and not the nitty gritty. Unless you've got a recent grad or a soon-to-be grad getting a PhD in Nutritional Sciences, like Chris Masterjohn, who is really up on the latest on the relationship between D, K2, A, magnesium and other cofactors, it's not safe to just mega dose on D. Besides that, you need a frickin test!

You also must consider your hereditary.

As far as I can determine from reading a good bit about this recently, African American people have lower vitamin D levels in their blood but higher active serum vitamin D levels. They still have very low D status over all. Just look how their lifestyle has drastically changed from their ancestors.

Below are a few studies that you should read. With respect to mega doses of any one vitamin, it's not good to think, given that African Americans are in the minority, that what's good for a Caucasian with a chronic disease would be the same dose. You really need to get a test and discuss with a very, very informed person regarding your own needs.

And also remember the obvious: nature doesn't work in isolation and neither does nutrition.

Racial/ethnic considerations in making recommendations for vitamin D for adult and elderly men and women.
http://www.ncbi.nlm.nih.gov/pubmed/15585802

Evidence for alteration of the vitamin D-endocrine system in blacks.
http://www.ncbi.nlm.nih.gov/pubmed/3839801

Vitamin D Economy in Blacks
http://onlinelibrary.wiley.com/doi/10.1359/jbmr.07s220/abstract

Two types of LDL cholesterol both are measured, but only the MGmin-LDL [glycated LDL] is "ultra-bad" it's from sugar and alcohol

When they measure your LDL cholesterol they are looking at two types in one. There's a light, buoyant kind that doesn't harm you and there's another that many are calling "ultra-bad" which is the sticky kind. Scientists call it "MGmin-LDL [glycated LDL]".

This is new research you can hear about at the two videos below:

http://www.youtube.com/watch?v=dBnniua6-oM&ob=av3e
1.5 hour edge of your seat action on sugar

http://www.youtube.com/watch?v=B56Gpf1f5_A
60 min CBS 14 min -Report on 1 April 2012 (yesterday)

The way to measure if you're at high risk for heart disease is to look at your triglycerides, not the LDL (which is the level of both the buoyant kind and the ultra bad).

http://health.usnews.com/health-news/diet-fitness/diabetes/articles/2011/05/27/scientists-discover-ultra-bad-cholesterol
http://www.mendeley.com/research/glycation-ldl-methylglyoxal-increases-arterial-atherogenicity-possible-contributor-increased-risk-cardiovascular-disease-diabetes-1/

This is from sugar, all forms, and alcohol - which is sugar. It's the fructose part of sugar that is very toxic.

If you want a sweet, eat a piece of fruit, not the juice. Don't replace sugar with fake sugar, splenda, aspartame, and the others are all VERY bad too.


“MGmin-LDL [glycated LDL] had decreased particle size, increased binding to proteoglycans, and increased aggregation in vitro. Cell culture studies showed that MGmin-LDL was bound by the LDL receptor but not by the scavenger receptor and had increased binding affinity for cell surface heparan sulfate–containing proteoglycan. Radiotracer studies in rats showed that MGmin-LDL had a similar fractional clearance rate in plasma to unmodified LDL but increased partitioning onto the aortal wall…A computed structural model predicted that MG modification of apoB100 induces distortion, increasing exposure of the N-terminal proteoglycan–binding domain on the surface of LDL. This likely mediates particle remodeling and increases proteoglycan binding.”

http://www.sciencedaily.com/releases/2011/05/110526204953.htm


Aspartame and Splenda DANGERS:

http://www.ncbi.nlm.nih.gov/sites/entrez?orig_db=PubMed&db=pubmed&cmd=Search&TransSchema=title&term=Journal%20of%20toxicology%20and%20environmental%20health.%20Part%20A[Jour]%20AND%202008[pdat]%20AND%20splenda

http://www.foodnavigator.com/Science-Nutrition/Splenda-may-damage-gut-bacteria-boost-weight-gain-study
http://www.sciencedaily.com/releases/2006/02/060213093019.htm

Health Problem: Brain damage/Cognitive skills disruption/Retardation/

Neurochemical changes in the brain/Behavioral and Mood Changes/Problems

1. Year Published: 1970
   Full Reference: Brain Damage in Infant Mice Following Oral Intake of Glutamate, Aspartate, or Cysteine; Nature 1970;227-609-610
   Funded By: Washington University
   Conclusion/Findings: Irreversible degenerative changes and acute neuronal necrosis
   Hyperlink to Study http://www.nature.com/nature/journal/v227/n5258/pdf/227609b0.pdf
2. Year Published: 2008
   Full Reference: Direct and Indirect Cellular Effects of Aspartame on the Brain. European Journal of Clinical Nutrition (2008) 62, 451-462; P. Humphries, E. Pretorius, and H. Naude
   Funded By: Not known
   Conclusion/Findings: Excessive aspartame ingestion might cause certain mental disorders, as well as compromised learning and emotional functioning
   Hyperlink to Study: http://www.newmediaexplorer.org/sepp/aspartamebrain.pdf
3. Year Published: 2007
   Full Reference: Life-Span Exposure to Low Doses of Aspartame Beginning During Prenatal Life Increases Cancer Effects in Rats, Morando Soffritti, Fiorella Belpoggi, Eva Tibaldi, Davide Degli Esposti, Michelina Lauriola; Environmental Health Perspectives, 115(9) Sep 2007; 115:1293-1297. doi:10.1289/ehp.10271.
   Funded By: Not known
   Conclusion/Findings: Carcinogenicity proven a second time; with effects increased when exposure to aspartame begins during fetal life.
   Hyperlink to Study: http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info:doi/10.1289/ehp.10271
4. Year Published: 1984
   Full Reference: Effects of Aspartame and Glucose on Rat Brain Amino Acids and Serotonin. Yokogoshi H, Roberst CH, Caballero B, Wurtman RJ. American Journal of clinical Nutrition. 1984 July, 40(1):1-7
   Funded By: MIT
   Conclusion/Findings: High aspartame doses can generate major neurochemical changes in rats, especially when consumed along with carbohydrate-containing foods
   Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/6204522
5. Year Published: 1984
   Full Reference: Revelance of Animal Studies to Human Safety. Olney, JW. Neurobehavioral Toxicology and Teratology. 1984; 6:455-462
   Funded By: MIT
   Conclusion/Findings: Excitotoxins, as used in foods today, may produce blood elevations high enough to cause damage to the nervous system of young children, damage which is not detectable at the time of occurrence but which may give rise to subtle disturbances in neuroendocrine function in adolescence and/or adulthood.
   Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/6152304
6. Year Published: 1996
   Full Reference: Increasing Brain Tumor Rates: Is There a Link to Aspartame? Olney JW, Farber NB, Spitznagel E, Robins LN. Journal of Neuropatholgy & Experimental Neurology. 1996 Nov; 55(11):1115-23
   Funded By: NIH
   Conclusion/Findings: Brain tumor incidence in the US implicates the introduction of aspartame into the American diet.
   Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/8939194
7. Year Published: 2000
   Full Reference: Glutamate and Aspartate Impair Memory Retention and Damage Hypothalamic Neurons in Adult Mice. Cheol Hyoung Park, Se Hoon Coi, et al. Toxicology Letters, Vol. 115, Issue 2, May 19, 2000, pp. 117-125
   Funded By: Not known
   Conclusion/Findings: Found that aspartate shortens the memory response, impairs memory retention and damages hypothalamic neurons in mice
   Hyperlink to Study: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCR-408BJC1-4&_user=10&_coverDate=05%2F19%2F2000&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view
   =c&_searchStrId=1456058577&
   _rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=395a2fc9d4ef0ffceeea475146341607
   &searchtype=a
8. Year Published: 2002
   Full Reference: Effect of Aspartame on N-Methyl-D Asparate Sensitive L-(311) Glutamate Binding Sites in Rat Brain Synpatic Membranes, AV Glushakov, DM Dennis, et al. Molecular Psychiatry, 2002, Vol. 7, No. 4, pp. 359-367.
   Funded By: University of Florida
   Conclusion/Findings: Shows that aspartate has a role in causing mental retardation, but the mechanism by which it does that is still unknown.
   Hyperlink to Study: http://www.nature.com/mp/journal/v7/n4/full/4000976a.html
9. Year Published: 2006
   Full Reference: The Effect of Aspartame Metabolites on Human Erythrocyte Membrane Acetylcholinesterase Activity. Stylianos Tsakiris, Aglaia Giannoulia-Karantana, et al., Pharmacological Research, Volv. 53, Issue 1, Jan. 2006. pp. 1-5.
   Funded By: Not known
   Conclusion/Findings: Found that high concentrations of aspartame can cause neurological symptoms, including memory and learning problems.
   Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/16129618
10. Year Published: 2008
    Full Reference: Direct and Indirect Cellular Effects of Aspartame on the Brain, P Humphries, E Pretorius and H Naude, European Journal of Clinical Nutrition , 2008, 62, 451-462
    Funded By: Not known
    Conclusion/Findings: Asserts that excessive aspartame ingestion might be involved in the pathogenesis of certain mental disorders (DSM-IV-TR 2000) and also in compromised learning and emotional functioning.
    Hyperlink to Study: http://www.nature.com/ejcn/journal/v62/n4/abs/1602866a.html
11. Year Published: 1986
    Full Reference: Evaluation of Reactions to Food Additives: The Aspartame Experience. MK Bradstock, MK Serdula, JS Marks, RJ Barnard, Nt Crane, PL Remington and FL Trowbridge. The American Journal of Clinical Nutrition. Vol. 43, pp. 464-469, 1986
    Funded By: Not known
    Conclusion/Findings: Identified some case reports in which the symptoms may be attributable to aspartame in commonly-consumed amounts. Headache, mood alterations (anxiety, agitation, irritability, or depression), insomnia, dizziness, and fatigue were the most frequently reported symptoms, with one case of a child in a double-blind test who became hyperactive after consuming products with aspartame.
    Hyperlink to Study: http://www.ajcn.org/cgi/reprint/43/3/464 and http://www.ajcn.org/cgi/content/abstract/43/3/464
12. Year Published: 1990
    Full Reference: Aspartame: Clinical Update, Potenza DP, el-Mallakh RS, Connecticut Medicine, 1990 Apr;54(4):235-6.
    Funded By: Not known
    Conclusion/Findings: Raises concern that so many reports of headaches, seizures, blindness, and cognitive and behavioral changes with long-term, high-dose aspartame have been reported that health officials need to be concerned.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2667892
13. Year Published: 1993
    Full Reference: Adverse Reactions to Aspartame: Double-Blind Challenge in Patients from a Vulnerable Population. Ralph G. Walton, Robert Hudak, Ruth J. Green-Waite. Psychiatry. July 1, 1993. Vol. 34, Issue 1, pp. 13-17.
    Funded By: Dept. of Psychiatry Northeastern Ohio,Universities College of Medicine and University Hospital of Cleveland
    Conclusion/Findings: Found that individuals with mood disorders are particularly sensitive to this artificial sweetener and its use in this population should be discouraged. In the clinical study, the project was halted by the Institutional Review Board after a total of 13 individuals had completed the study because of the severity of reactions within the group of patients with a history of depression
    Hyperlink to Study: http://www.biologicalpsychiatryjournal.com/article/0006-3223%2893%2990251-8/abstract
14. Year Published: 1986
    Full Reference: Seizure and Mania After High Intake of Aspartame
    Funded By: Jamestown General Hospital, Jamestown, New York
    Conclusion/Findings: Case report of a woman who drank in excessive of 1 gallon per day of iced tea sweetened with aspartame, resulting in manic episode and seizure that led to hospitalization.
    Hyperlink to Study: http://psy.psychiatryonline.org/cgi/pdf_extract/27/3/218
15. Year Published: 1991
    Full Reference: Effect of Aspartame and Protein, Administered in Phenylalanine-Equivalent Doses, on Plasma Neutral Amino Acids, Aspartate, Insulin and Glucose in Man, Svend E. Moller; Pharmacology & Toxicology, Vol. 68, Issue 5, pp. 408-412.
    Funded By: Clinical Research Laboratory, Denmark
    Conclusion/Findings: The study showed that the intake of aspartame in a not unrealistically high dose produced a marked and persistent increase of the availability of Phe to the brain, which was not observed after protein intake. The study indicated, furthermore, that Phe was cleared faster from the plasma after consumption of protein compared with aspartame.
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/122214234/abstract
16. Year Published: 1994
    Full Reference: Effects of Diets High in Sucrose or Aspartame on the Behavior and Cognitive Performance of Children. Mark L. Wolraich, Scott D. Lingren, et al. New England Journal of Medicine, Feb. 3, 1994; pp. 330:301-307
    Funded By: Not known
    Conclusion/Findings: Reported that it is possible that there are some children who respond adversely to sugar or aspartame.
    Hyperlink to Study: http://www.nejm.org/doi/full/10.1056/NEJM199402033300501#articleResults
17. Year Published: 1985
    Full Reference: Loss of Intellectual Function in Children with Phenylketonuria After Relaxation of Dietary Phenylalanine Restriction, Margretta R. Seashore, Estelle Friedman, Robert A. Novelly P, Vijaya Bapat MD. Pediatrics vol. 75, No. 2, Feb. 1985, pp. 226-232
    Funded By: Not known
    Conclusion/Findings: Shows decrease in intellectual function in children with PKU who have phenylalnine introduced into their diets.
    Hyperlink to Study: http://pediatrics.aappublications.org/cgi/content/abstract/75/2/226
18. Year Published: 1987
    Full Reference: Aspartame Effects on Brain Serotonin, RI Wurtman, Letter in American Journal of Clinical Nutrition, 1987 April; 45(4):799-803
    Funded By: MIT
    Conclusion/Findings: Argues that using rodents to disprove aspartame’s harm to humans is not relevant, and that it reacts more negatively in humans than in mice
    Hyperlink to Study: http://www.ajcn.org/cgi/reprint/45/4/799.pdf
19. Year Published: 1986
    Full Reference: Acute Effects of Oral or Parenteral Aspartame on Catecholamine Metabolism in Various Regions of Rat Brain, Hidehiko Yokogoshi and Richard J. Wurtman, The Journal of Nutrition, November 1986
    Funded By: MIT
    Conclusion/Findings: Found higher plasma tyrosine and phenylalanine ratios and other effects on the brain.
    Hyperlink to Study: http://jn.nutrition.org/cgi/content/abstract/116/3/356
20. Year Published: 1992
    Full Reference: Aspartame Exacerbates EEG Spike Wave Discharge in Children with Generalized Absence Epilepsy, PR Camfield, CS Camfield, JM Dooley, et al;
    Funded By: Ontario Ministry of Health
    Conclusion/Findings: Neurology 1992:42:1000
    Hyperlink to Study: http://www.neurology.org/cgi/content/abstract/42/5/1000
21. Year Published: 1993
    Full Reference: The Effect of Food Chemicals on Cell Aging of Human Diploid Cells in Vitro Culture, Kasamaki A and Urasawa S, The Journal of Toxicological Sciences, 1993 Aug; 18(3):143-53
    Funded By: Toxicological Sciences, 1993 Aug; 18(3):143-53. Sapporo
    Conclusion/Findings: Showed aging of cells when treated with aspartame.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/8246307
22. Year Published: 1994
    Full Reference: Neuropharmacological Evaltuation of Movement Disorders that are Adverse Reactions to Specific Foods Including Aspartame, John W. Gerrard, J Steven Richardson and Jeffrey Donat; International Journal of Neuroscience, 1994, Vol. 76, No. 1-2, pp. 61-69
    Funded By: University of Saskatchewan, Canada
    Conclusion/Findings: Shows that in susceptible individuals, certain foods or additives, including aspartame, can trigger movement disorders through an action on dopamine and other neurotransmitter pathways in the brain.
    Hyperlink to Study: http://informahealthcare.com/doi/abs/10.3109/00207459408985992
23. Year Published: 1995
    Full Reference: Effects of Aspartame on 45 CA Influx and LDH Leakage from Nerve Cells in Culture, Sonnewald U, Unsgard G, Petersen SB; Neuropharmacology and Neurotoxicology, 1995, Vol. 6, Issue 2
    Funded By: Research Council of Norway
    Conclusion/Findings: Showed signs of severe cell damage and other neurological events with aspartame.
    Hyperlink to Study: http://journals.lww.com/neuroreport/Abstract/1995/01000/Effects_of_aspartame_on_45Ca_influx_and_LDH.23.aspx
24. Year Published: 1996
    Full Reference: Increasing Brain Tumor Rates: Is There A Link to Aspartame? JW Olney, Nuri B Farber, et al.; Journal of Neuropathology & Experimental Neurology, Nov. 1996, Vol. 55, Issue 11
    Funded By: NIH
    Conclusion/Findings: Evidence implicates aspartame as a causative agent of high incidence of brain tumors in aspartame-fed rats.
    Hyperlink to Study: http://journals.lww.com/jneuropath/Abstract/1996/11000/Increasing_Brain_Tumor_Rates__Is_There_a_Link_to.2.aspx
25. Year Published: 1998
    Full Reference: Formaldehyde Derived from Dietary Aspartame Binds to Tissues Components in Vivo, C. Trocho, R. Pardo, I. Rafecas, et al
    Funded By: University of Barcelona, Spain
    Conclusion/Findings: Showed that aspartame consumption may constitute a hazard because of its contribution to the formation of formaldehyde adducts.
    Hyperlink to Study: http://www.wnho.net/formaldehyde_from_aspartame.pdf

Health Problem: Headache/Migraines

26. Year Published: 1985
    Full Reference: Aspartame: Possible Effect on Seizure Susceptibility. Wurtman, RJ. Lancet. Vol. 2, no. 8463, 1060 p. 1985
    Funded By: MIT
    Conclusion/Findings: Woman who drank large amounts of Diet Coke and other aspartame-flavored beverages experienced headaches, nausea, visual hallucinations, and a grand-mal seizure.
    Hyperlink to Study: http://md1.csa.com/partners/viewrecord.php?requester=gs&collection=ENV&recid=1354938&q=Aspartame%3A+Possible+Effects+on+Seizure+Suspectibility&
    uid=789675711&setcookie=yes
27. Year Published: 1987
    Full Reference: The Effect of Aspartame on Migraine Headache. Shirley M. Koehler, Alan Glaros. Headache: The Journal of Head and Face Pain. Vol 28, Issue 1, Nov. 12, 1987
    Funded By: Not known
    Conclusion/Findings: Ingestion of aspartame by migraine sufferers causes significant increases in headache frequency
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/119449495/abstract
28. Year Published: 1998
    Full Reference: Aspartame as a Dietary Trigger of Headache. Richard B. Lipton, MD, Lawrence C. Newman, MD, Joel S. Cohen, MD, Seymour Solomon, MD. The Journal of Head and Face Pain. Vol. 29, Issue 2, pp. 90-92. Sept. 1998
    Funded By
    Conclusion/Findings: Finds that aspartame may be an important dietary trigger of headache in some people.
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/119429393/abstract
29. Year Published: 1991
    Full Reference: Platelet Glycine, Glutamate and Aspartate in Primary Headache, D'Andrea, G., et al., 1991. Cephalalgia, Vol. 11, pp. 197-200.
    Funded By: Not known
    Conclusion/Findings: High levels of these amino acids were found in patients with migraine with aura compared to normal subjects and other headache groups
    Hyperlink to Study: http://cep.sagepub.com/content/11/4/197.abstract
30. Year Published: 1997
    Full Reference: Chewing Gum Headaches, Blumenthal, H.J., D.A. Vance, Headache, Volume 37, Number 10, pages 665-666. 1997
    Funded By: Department of Neurology, University of Oklahoma College of Medicine, Tulsa
    Conclusion/Findings: Chewing gum with aspartame provokes headaches
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/119166706/abstract
31. Year Published: 2003
    Full Reference: The Diet Factor in Pediatric and Adolescent Migraine, Millichap JG, Yee MM. Pediatric Neurology, 2003 Jan;28(1):9-15
    Funded By: Not known
    Conclusion/Findings: Aspartame is one of the substances that trigger migraines in children and adolescents
    Hyperlink to Study: http://www.drcordas.com/education/Headaches/1doc.pdf
32. Year Published: 1994
    Full Reference: Aspartame Ingestion and Headaches: a Randomized Crossover Trial. S. K. Van Den Eeden, PhD, T. D. Koepsell, MD, MPH, W. T. Longstreth, Jr., MD, MPH, G. van Belle, PhD, J. R. Daling, PhD and B. McKnight, PhD, American Academy of Neurology, Neurology. 1994;44:1787
    Funded By: University of Washington
    Conclusion/Findings: This experiment provides evidence that, among individuals with self-reported headaches after ingestion of aspartame, a subset of this group report more headaches when tested under controlled conditions. It appears that some people are particularly susceptible to headaches caused by aspartame and may want to limit their consumption.
    Hyperlink to Study: http://www.neurology.org/cgi/content/abstract/44/10/1787?ijkey=4b59bcfcba6c01af70844762469ca00f7f358c5f&keytype2=tf_ipsecsha
33. Year Published: 1990
    Full Reference: The Concept of Migraine as a State of Central Neuronal Hyperexcitability, KMA Welch, et all, 1990. Headache, Vol. 8, No. 4, pp 817-828.
    Funded By: Not known
    Conclusion/Findings: Finds that aspartate can cause migraine with aura associated with a state of central neuronal hyperexcitability
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/1979655
34. Year Published: 2001
    Full Reference: Migraine MLT-Down: An Unusual Presentation of Migraine in Patients with Aspartame-Triggered Headaches. Lawrence C. Newman, Richard B. Lipton, Headache: The Journal of Head and Face Pain, Vol. 41, Issue 9, pp. 899-901
    Funded By: The Headache Institute, St. Lukes-Roosevelt Hospital Center, New York
    Conclusion/Findings: Reports that aspartame may trigger headaches in susceptible individuals, and can worsen an ongoing attack of migraine.
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/120697481/abstract
35. Year Published: 1988
    Full Reference: Aspartame as a Dietary Trigger of Headache, Richard B. Lipton, Lawrence C. Newman, Joel S. Cohen, Seymour Solomon, Headache: The Journal of Head and Face Pain, Vol. 29, Issue 2, pp. 90-92
    Funded By: Department of Neurology, Albert Einstein College of Medicine, Bronx, NY
    Conclusion/Findings: Reports that some patients with migraines reported aspartame as a trigger three times more often than those with other types of headache.
    Hyperlink to Study: http://www3.interscience.wiley.com/journal/119429393/abstract

---

Health Problem: Increase in hunger, body weight, BMI

36. Year Published: 1991
    Full Reference: Chen, L. N., and Parham, E. S. “College Students’Use of High-Intensity Sweeteners Is Not Consistently Associated with Sugar Consumption.” J Am Diet Assoc. 91(1991): 686–90
    Funded By: Department of Human and Family Resources at Northern Illinois University
    Conclusion/Findings: In a study of high-intensity artificial sweeteners performed on college students, there was no evidence that artificial sweetener use was associated with a decrease in their overall sugar intake. These results indicate that eating arti­ficial sweeteners simply perpetuates a craving for sweets, and overall sugar consumption is not reduced—leading to further problems controlling your weight
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2040783
37. Year Published: 2005
    Full Reference: “New Analysis Suggests ‘Diet Soda Paradox’ – Less Sugar, More Weight.” UT Health Center San Antonio Press Release. June 14, 2005 · Volume: XXXVIII · Issue: 24
    Funded By: University of Texas Health Science Center at San Antonio
    Conclusion/Findings: In 2005, data gathered from the 25-year long San Antonio Heart Study also showed that drinking diet soft drinks increased the likelihood of serious weight gain – far more so than regular soda.

According to Sharon Fowler, M.P.H:
“On average, for each diet soft drink our participants drank per day, they were 65 percent more likely to become overweight during the next seven to eight years, and 41 percent more likely to become obese.”
Hyperlink to Study: http://www.uthscsa.edu/hscnews/singleformat2.asp?newID=1539

38. Year Published: 2004
    Full Reference: “A Pavlovian Approach to the Problem of Obesity,” Davidson, TL and Swithers Se, International Journal of Obesity and Related Metabolic Disorders 2004 Jul;28(7):933-5.
    Funded By: Department of Psychological Science, Ingestive Behavior Research Center, Purdue University
    Conclusion/Findings: Found that rats fed artificially sweetened liquids ate more high-calorie food than rats fed high-caloric sweetened liquids. The researchers believe the experience of drinking artificially sweetened liquids disrupted the animals' natural ability to compensate for the calories in the food.
    Hyperlink to Study:
    http://www.ncbi.nlm.nih.gov/pubmed?term=933[page]+AND+2004/07[pdat]+AND+Davidson[author]&cmd=detailssearch
39. Year Published: 1988
    Full Reference: Uncoupling Sweet Taste and Calories, Comparison of Glucose and Three Intense Sweeteners on Hunger and Food Intake. Peter J. Rogers, Jo-ASnne Carlyle, Andrew J. Hill and John E. Blundell. Physiology & Behavior. Vol. 43; Issue 5, 1988. pp. 547-552
    Funded By: Biopsychology Group, Psychology Dept., University of Leeds, Leeds UK
    Conclusion/Findings: Intense sweeteners can produce significant changes in appetite, with aspartame causing the most pronounced effects.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/3200909
40. Year Published: 1990
    Full Reference: Oral Stimulation with Aspartame Increases Hunger, Michael G. Tordoff and Annette M. Alleva, Physiology & Behavior, Vol. 47, Issue 3, March 1990; pp. 555-559.
    Funded By: Monell Chemical Senses Center, Philadelphia
    Conclusion/Findings: Showed that aspartame can increase the feeling of hunger
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2359769

41. Year Published: 2010
    Full Reference: Gain Weight by “Going Diet?” Artificial Sweeteners and the Neurobiology of Sugar Cravings. Qing Yang, Yale Journal of Biological Medicine, 2010 June; 83(2): 101-108. Department of Molecular, Cellular and Developmental Biology
    Funded By: Yale University
    Conclusion/Findings: Several large scale prospective cohort studies found positive correlation between artificial sweetener use and weight gain. When matched for initial body mass index (BMI), gender, ethnicity, and diet, drinkers of artificially sweetened beverages consistently had higher BMIs. Similar observations have been reported in children. Artificial sweeteners, precisely because they are sweet, encourage sugar craving and sugar dependence.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892765/?tool=pubmed

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Other Health Problems: Multiple symptoms including retinal damage, disruption of odor-associated learning, miscellaneous toxicity problems, elevations in plasma, pre-term delivery, rise in serum methanol

42. Year Published: 1985
    Full Reference: A Metabolite of Aspartame Inhibits Angiotensin Converting Enzyme. Grobelny D, Galardy RE. Biochemical & BioPhysical Research Communications. 1985: 128(2):960-964.
    Funded By: University of Kentucky
    Conclusion/Findings: Possibility exists that consuming large amounts of aspartame inhibits angiotensin converting enzyme
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2986632
43. Year Published: 1986
    Full Reference: Serum Methanol Concentrations in Rats and in Men after a Single Dose of Aspartame," Davoli, E., et al., 1986. Food and Chemical Toxicology, Vol. 24, No. 3, pp. 187-189
    Funded By: Not known
    Conclusion/Findings: Both treatments caused a temporary rise in serum methanol. Methanol is a highly toxic alcohol commonly found in automobile windshield washer solvent, gas line antifreeze, copy machine fluid, fuel for small stoves, paint strippers, and as an industrial solvent.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/3957170
44. Year Published: 1977
    Full Reference: Effect of a Dipeptide, Aspartame, on Lactic Acid Production in Human Whole Saliva. Y. Mishiro and H. Kaneko. Journal of Dental Research, 1977 56(11):1427
    Funded By: Nippon Dental University, Japan
    Conclusion/Findings: Aspartame affects levels of saliva lactation and pH levels.
    Hyperlink to Study: http://jdr.sagepub.com/content/56/11/1427.full.pdf
45. Year Published: 2010
    Full Reference: Intake of Artificially Sweetened Soft Drinks and Risk of Preterm Delivery: a Prospective Cohort Study of 59,334 Danish Pregnant Women. Halldorsson TI, Strom M, Petersen SB, Olsen SF, American Journal of Clinical Nutrition, June 30, 2010
    Funded By: Center for Fetal Programming, Division of Epidemiology, Statens serum Institute, Denmark
    Conclusion/Findings: There was an association between intake of artificially sweetened carbonated and noncarbonated soft drinks and an increased risk of preterm delivery.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/20592133
46. Year Published: 1987
    Full Reference: Effects of Oral Aspartame on Plasma Phenylalanine in Humans and Experimental Rodents, RJ Wurtman and TJ Maher. Journal of Neural Transmission, Vol. 70, Nos. 1-2, March 1987, pp. 169-173
    Funded By: MIT
    Conclusion/Findings: Aspartame causes greater elevations in plasma phenylalanine than plasma tyrosine in humans.
    Hyperlink to Study: http://www.springerlink.com/content/l148w94568vt33hw/
47. Year Published: 1986
    Full Reference: Acute Effects of Aspartame on Systolic Blood Pressure in Spontaneously Hypertensive Rats. P.J. Kiritsy and T.J. Maher. Journal of Neural Transmission, Vol 66, No. 2, June 1986, pp 121-128
    Funded By: Neuropharmacology Laboratory, Dept. of Pharmacology, Massachusetts College of Pharmacy and Allied Health Science, Boston
    Conclusion/Findings: Aspartame elevates blood and brain tyrosine levels, and cause neurochemical changes that lead to tyrosine-induced drop in blood pressure.
    Hyperlink to Study: http://www.springerlink.com/content/p33231m752721l5x/?p=41116b2cb5284004987aaa24f8a945c9&pi=37
48. Year Published: 1986
    Full Reference: Aspartame-Induced Uricaria. Anthony Kulczycki Jr., M.D. Annals of Internal Medicine. Feb. 1, 1986. Volv 104. No 2. pp. 207-208
    Funded By: Grant support NIH.
    Conclusion/Findings: Aspartame-induced urticaria confirmed by double-blind challenge.
    Hyperlink to Study: http://www.annals.org/content/104/2/207.extract
49. Year Published: 1989
    Full Reference: Behavioral Assessment of the Toxicity of Aspartame, Mark D. Holder, Pharmacology Biochemistry & Behavior, Vol. 32, pp. 17-26
    Funded By: Memorial University of Newfoundland
    Conclusion/Findings: Found that aspartame may have adverse effects when intrapeitoneally injected.
    Hyperlink to Study: http://pluto.huji.ac.il/~msrazy/PDF/HolderPBB89.pdf
50. Year Published: 1989
    Full Reference: Impaired Performance on Odor-Aversion Testing Following Prenatal Aspartame Exposure in the Guinea Pig, Diana L. Dow-Edwards, Louise A. Scribani and Edward P. Riley, Neuurotoxicity and Teratology, Vol. 11, Issue 4, July-August 1989, pp. 413-416
    Funded By: Dept. of Neurosurgery State University, New York
    Conclusion/Findings: These data indicate that aspartame exposure at 500 mg/kg throughout gestation disrupts odor-associative learning in 15-day-old guinea pigs.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2796897
51. Year Published: 2006
    Full Reference: Aspartame Products as a Potential Danger to Infants, Children & Future Generations, Dr. HJ Roberts, director, Palm Beach Institute for Medical Research
    Funded By: No funding
    Conclusion/Findings: Aspartame causes a variety of disease in children including headaches, convulsions, unexplained visual loss, rashes, asthma, gastrointestinal problems, obesity, marked weight loss, hypoglycemia, diabetes, addiction (probably largely due to the methyl alcohol), hyperthyroidism, and a host of neuropsychiatric features. The latter include extreme fatigue, irritability, hyperactivity, depression, antisocial behavior (including suicide), poor school performance, the deterioration of intelligence, and brain tumors.
    Hyperlink to Study: http://www.rense.com/general70/duut.htm
52. Year Published: 1986
    Full Reference: Plasma Amino Acid Levels After Single Dose Aspartame Consumption in Phenylketonuria Mild II Hyperphenylalaninemia and Heterozygous State for Phenylkeonuria. The Journal of Pediatrics, Vol. 109, No. 4, pp. 668-671, October 1986.Benjamin Caballero, Barbara E. Mahon, Frances J. Rohr, Harvey L. Levy, and Richard J. Wurtman. M.D
    Funded By: MIT
    Conclusion/Findings: Plasma phenylalanine concentrations may increase to unacceptable levels when patients with PKU on phenylalanine-restricted diets consume aspartame-containing soft drinks or after loading doses of the sweetener
    Hyperlink to Study: http://wurtmanlab.mit.edu/static/pdf/673.pdf
53. Year Published: 1985
    Full Reference: Aspartame-Induced Granulomatous Panniculitis. Nelson Lee Novick, MD. Annals of Internal Medicine., Vol 102, No. 2, pp. 206-207
    Funded By: Mt. Sinai Medical Center; New York
    Conclusion/Findings: This report describes the first confirmed case of aspartame-induced granulomatous panniculitis

Hyperlink to Study: http://www.annals.org/content/102/2/206.short

54. Year Published: 1984
    Full Reference: Aspartame: Methanol and the Public Health. Woodrow C.Monte. Journal Applied Nutrition 36(1):42-54
    Funded By
    Conclusion/Findings: Consumption of aspartame sweetened drinks at levels commonly used to replace lost fluid during exercise yields methanol intake between 15 and 100 times normal intakes.
    Hyperlink to Study: http://www.dorway.com/wmonte.txt
55. Year Published: 1989
    Full Reference: Excitoxins: A Possible New Mechanism for the Pathogenesis of Ischemic Retinal Damage, George H. Bresnick, Archives of Opthalmology, 1989; 107(3):339-341
    Funded By: NIH
    Conclusion/Findings: Reports that aspartame is a possible mechanism to cause retinal damage.
    Hyperlink to Study: http://archopht.ama-assn.org/cgi/content/summary/107/3/339
56. Year published: 1987
    Full reference: Plasma Amino Acid Concentrations in Normal Adults Administered Aspartame in Capsules or Solution: Lack of Bioequivalence, Lewis D. Stegin, L.J. Filer Jr, E.F. Bell, and E.E. Ziegler, Metabolism Volume 36, Issue 5 May 1987, Pages 507-512
    Funded by: Supported in part by a grant-in-aid from G.D. Searle
    Conclusion/Findings: The data indicate different plasma phenylalanine and aspartate pharmacokinetics between aspartame in solution and capsule administration of aspartame. Peak plasma phenylalanine levels were significantly higher and were reached significantly earlier when aspartame was administered in solution than when it was administered in capsules. Administration in solution also produced a significantly higher ratio of plasma phenylalanine concentration to the sum of the plasma concentrations of the other large neutral amino acids. Similarly, peak plasma aspartate concentrations were significantly higher and were reached significantly earlier when aspartame was administered in solution.
    Hyperlink to study: http://www.ncbi.nlm.nih.gov/pubmed/3574137
57. Year published: 1984
    Full reference: Evaluation of Consumer Complaints Related to Aspartame Use, MK Bradstock, MK Serdula, JS Marks, RJ Barnard, NT Crane, PL Remington and FL Trowbridge, American Journal of Clinical Nutrition, November 1984, Vol 43, 464-469
    Funded by: Division of Nutrition, Center for Health Promotion and Education, Centers for Disease Control
    Conclusion/Findings: In some case reports, the symptoms may be attributable to aspartame in commonly-consumed amounts
    Hyperlink to study: http://www.ajcn.org/cgi/content/abstract/43/3/464

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Health Problem: Seizures/Convulsions

58. Year Published: 1987
    Full Reference: Possible Neurologic Effects of Aspartame, a Widely Used Food Additive; Timothy J. Maher and Richard J. Wurtman. Environmental Health Perspectives, Vol. 75, pp 53-57, 1987
    Funded By: MIT and Federal Government
    Conclusion/Findings: Shows that aspartame can induce seizures
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474447/pdf/envhper00434-0053.pdf
59. Year Published: 1991
    Full Reference: Interspecies and Interstrain Studies on the Increased Susceptibility to Metrazol-Induced Convulsions in Animals given Aspartame, L. Diomede, M. Romano, et al, Milan, Italy, Food and Chemical Toxicology, Vol. 29, Issue 2, 1991; pp. 101-106
    Funded By: Istituto di Richerche, Milan, Italy
    Conclusion/Findings: Showed that they are more susceptible to convulsions when given higher doses of aspartame
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/2010138

Letters and Other Commentary from Health Sources

60. Year Published: 1995
    Full Reference: Emerging Facts about Aspartame. Dr. J. Barua, Dr. A Bal. Journal of the Diabetic Association of India. 1995; Vol. 35, No. 4
    Funded By: No funding
    Conclusion/Findings: Cites numerous studies showing dangers of aspartame
    Hyperlink to Study: http://basichealthinfo.weebly.com/uploads/4/2/5/9/425984/article-on-aspartame.pdf
61. Year Published: 2004
    Full Reference: Aspartame: An FDA-Approved Epidemic, HJ Roberts, Palm Beach Institute for Medical Research.
    Funded By: No funding
    Conclusion/Findings: Cites thousands of consumer complaints to the FDA that include serious adverse events, that the FDA and CDC refused to acknowledge as substantive.
    Hyperlink to Study: http://www.aspartame.ca/epidemic-s3.pdf
62. Year Published: 1991
    Full Reference: Recurrent Vulvovaginitis Resulting from Heavy Dietary Use of Aspartame, Strathman I, The Journal of Reproductive Medicine. 1991 Aug;36(8):572
    Funded By: No funding
    Conclusion/Findings: (This is a letter; title implies that vulvovaginitis was triggered by heavy use of aspartame)
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/1941798
63. Year Published: 1985
    Full Reference: Interaction of Aspartame and Carbohydrates in an Eating Disordered Patient. Ferguson A Jr. A Letter in the American Journal of Psychiatry. 1985, Feb. 142(2):271
    Funded By: Not applicable
    Conclusion/Findings: Reports a clinical case where aspartame combined with carbohydrates causes headaches and other symptoms typical of elevated CNS level of tyrosine.
    Hyperlink to Study: http://ajp.psychiatryonline.org/cgi/reprint/142/2/271a.pdf
64. Year Published: 1995
    Full Reference: A Health Alert: Emerging Facts About Aspartame, Dr. J Barua, Dr. A Bal, The Journal of the Diabetic Association of India, 1995: Vol. 35, No. 4
    Funded By: No funding
    Conclusion/Findings: This article summarizes a number of other people’s studies on aspartame.
    Hyperlink to Study: http://smfi.is/media/misc/article-on-aspartame.pdf
65. Year Published: 1996
    Full Reference: Aspartame as a Cause of Allgeric Reactions, Including Anaphylaxis, Archives of Internal Medicine, 1996; 156(9):1027
    Funded By: Not known
    Conclusion/Findings: Letter arguing that aspartame should have been included as a causative agent of allergic reactions. Cites FDA 7,300-person database of complaints.
    Hyperlink to Study: http://archinte.ama-assn.org/cgi/content/summary/156/9/1027-a
66. Year Published: Updated April 23, 2008
    Full Reference: Is Aspartame Safe? From an FDA Q&A about aspartame
    Funded By: Not applicable
    Conclusion/Findings: While denying that aspartame is an allergen, the FDA says: However, certain people with the genetic disease phenylketonuria (PKU), those with advanced liver disease, and pregnant women with hyperphenylalanine (high levels of phenylalanine in blood) have a problem with aspartame because they do not effectively metabolize the amino acid phenylalanine, one of aspartame's components. High levels of this amino acid in body fluids can cause brain damage. Therefore, FDA has ruled that all products containing aspartame must include a warning to phenylketonurics that the sweetener contains phenylalanine.
    Hyperlink to Study: http://answers.hhs.gov/questions/3011
67. Year published:
    Full reference: Scientific Abuse in Methanol/Formaldehyde Research Related to Aspartame
    Funded by: no funding
    Conclusion/Findings: Exposes studies “proving” safety of aspartame as deceptive, erroneous, and based on industry research using outdated plasma methanol measuring tests. No date of publication.
    Hyperlink to Study: http://thetruthaboutstuff.com/pdf/%2847%29%20Scientific%20Abuse%20in%20Methanol.pdf

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Health Problem: Cancer

68. Year published: 2010
    Full reference:Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice. American Journal of Industrial Medicine December 2010; 53(12): 1197-1206
    Conclusion/Findings:The results of the present study confirm that [aspartame] is a carcinogenic agent in multiple sites in rodents, and that this effect is induced in two species, rats (males and females) and mice (males). Autopsies revealed a significantly increased risk of liver and lung cancer.
    Hyperlink to Study: http://www.ncbi.nlm.nih.gov/pubmed/20886530